M
mesoestetic® Depigmentation · Chichester

Cosmelan in Chichester

Pigmentation that keeps coming back isn’t a surface problem. Cosmelan treats melasma, sun spots, post-acne marks and uneven tone at the source: it fades the look of the pigment you can see and helps regulate the cells that keep producing it.

One session in clinic, then a guided home programme of 6 weeks to 6 months, depending on your pigmentation, prescribed and reviewed by Morgan French, Registered Nurse and Independent Prescriber. Suitable for every skin tone.

mesoestetic cosmelan 1 and cosmelan 2, Cosmelan depigmentation treatment at Mediluxe Clinic, Chichester
From £595
In clinic
1 session, then home care
Programme
6 weeks to 6 months
Downtime
7 days of healing & peeling
Skin types
All skin tones, face only
At home
Skincare plan

Why does pigmentation keep coming back?

Dark patches start deep in the skin, in pigment cells called melanocytes. Sun, hormones, inflammation and genetics switch them into overdrive, so they overproduce melanin and push it up to the surface, where it collects as melasma, sun spots and post-acne marks.

Peels, lasers and brightening serums can lift the surface pigment, but if those cells are still overactive, the marks return, often after the next summer. Cosmelan is built differently: an intensive correction in clinic, then months of regulation at home that calm pigment production at its source.

It is mesoestetic’s professional depigmentation method, used on more than a million patients worldwide, and Mediluxe uses the same mesoestetic range for your treatment and your home care.

Who Cosmelan suits

  • Melasma and hormonal pigmentation
  • Sun spots, age spots and freckles
  • Post-acne marks and post-inflammatory pigmentation
  • Uneven, patchy or dull skin tone
  • Pigmentation that hasn’t shifted with serums, peels or laser
The science

Treated at the source.

  1. 01 · Correct

    Lifts existing pigment

    The cosmelan 1 mask speeds up skin renewal, clearing pigment from the surface layers of the skin.

  2. 02 · Regulate

    Calms the pigment cells

    Cosmelan 2 works inside the melanocyte. It inhibits tyrosinase, the enzyme that makes melanin, and slows the transfer of pigment to the skin’s surface.

  3. 03 · Clear & protect

    Helps stop it coming back

    It helps the skin break down melanin already stored in its cells, while daily SPF and a maintenance routine help keep new pigment from forming.

Melanin synthesis*
−90%
Tyrosinase activity*
−56%
Patients worldwide
More than 1 million
Skin types
Fitzpatrick I–VI

The 2024 Cosmelan formula is built around two patented mesoestetic® technologies: melaphenone®, designed to inhibit tyrosinase with high precision, and cosmesome®, an encapsulated apigenin and phloretin complex that helps self-regulate melanin overproduction. They work alongside proven depigmenting actives including kojic acid, niacinamide, hexylresorcinol, retinol, vitamin C and phytic acid.

*Laboratory results in melanocyte cell culture (−90%: cosmelan® vs control; −56%: melaphenone®), mesoestetic® Pharma Group. Laboratory results do not predict individual clinical outcomes.

Your treatment journey

What to expect.

  1. 01

    Consultation & preparation

    Morgan assesses your skin and pigmentation and recommends a programme of 6 weeks to 6 months. Avoid the sun for 15 days beforehand; a Melanostop Tranex peel 15 days before is recommended to prepare the skin.

  2. 02

    Your clinic session

    A morning appointment, finished by 1pm. Your skin is cleansed and degreased, delicate areas are protected, and the cosmelan 1 mask is applied. You go home wearing it.

  3. 03

    Mask off & healing

    You wash the mask off with lukewarm water 6 to 8 hours later, timed to your skin. The first 7 days are for soothing and repair; redness, warmth and peeling are normal.

  4. 04

    Home programme & results

    From day 7 you use cosmelan 2 twice a day. Tone keeps evening out over the following months, with reviews every 6 weeks and a maintenance plan from month 7.

Results

Before & after, day by day.

Drag the line to compare.

Day 120, Sun damage · day 0 to day 120, cosmelan®, mesoestetic case study
Day 0, Sun damage · day 0 to day 120, cosmelan®, mesoestetic case study
Uneven Tone Sun damage · day 0 to day 120 · cosmelan®
Day 180, Day 0 to day 180, cosmelan®, mesoestetic case study
Day 0, Day 0 to day 180, cosmelan®, mesoestetic case study
Melasma Day 0 to day 180 · cosmelan®
Day 180, Day 0 to day 180, cosmelan®, mesoestetic case study
Day 0, Day 0 to day 180, cosmelan®, mesoestetic case study
Post-Acne Marks Day 0 to day 180 · cosmelan®

Results from mesoestetic® case studies, not Mediluxe Clinic clients. Individual results vary, and your programme is chosen at consultation.

Why Cosmelan

Trusted by professionals, proven on every skin.

A long track record

Over a million patients worldwide have been treated with the cosmelan® method, one of the most established professional depigmentation treatments available.

Short and long-term results

A comprehensive treatment that corrects existing pigmentation quickly, then helps keep hyperpigmentation under control over the long term.

Every skin type

Efficacy studies support its results across all skin types, phototypes and types of hyperpigmentation.

Visible from week one

Patients report high satisfaction, with visible results from the first week of treatment.

Recommended by experts

Thousands of professionals treat hyperpigmentation with the cosmelan® method and recommend it to their patients.

Nurse-led from start to finish

Prescribed, applied and reviewed by Morgan French, Registered Nurse and Independent Prescriber, with reviews every 6 weeks of your programme.

Claims as stated by mesoestetic® Pharma Group. Individual results vary.

Pricing

Cosmelan prices.

mesoestetic cosmelan 2, Cosmelan at Mediluxe Clinic, Chichester

6-Week Programme · Lighter or recent pigmentation

Your in-clinic cosmelan 1 session, the 7-day healing phase and one 6-week pot of cosmelan 2, with your home kit and reviews at day 1, day 7 and week 6. Ideal for sun spots, post-acne marks and uneven tone.

  • 6-week programme £595
  • Additional 6 weeks: Cosmelan home care pack £220

Each home care pack contains cosmelan 2, melan recovery and melan 130 pigment control, and lasts a further 6 weeks to keep improving your pigmentation. One clinic session, then home care. Suitable for all skin types.

mesoestetic cosmelan home pack, Cosmelan at Mediluxe Clinic, Chichester

6-Month Programme · Melasma & deep pigmentation

The full mesoestetic protocol behind the day-180 results above. Your clinic session and healing phase, then six months at home with your starter kit plus three Cosmelan home care packs, a review every 6 weeks and your month-7 maintenance plan. Includes your Melanostop Tranex preparation peel, worth £120.

  • 6-month programme £1,295

Recommended for melasma, hormonal and long-standing pigmentation. Saves £80 against the 6-week programme plus three home care packs and the preparation peel.

mesopeel® melanostop tranex, Cosmelan at Mediluxe Clinic, Chichester

Preparation Peel · Recommended before Cosmelan

mesopeel® Melanostop Tranex, 15 days before your Cosmelan session, to prepare the skin and enhance your result.

  • Single treatment £120

Included in the 6-Month Programme.

Your programme is confirmed at consultation, depending on your pigmentation.

Home maintenance

Your routine, stage by stage.

After one session in clinic, your result is built at home. Following your routine closely, and wearing SPF every day, is the single biggest factor in how well and how long your pigmentation stays away.

cosmelan 2, mesoestetic skincare at Mediluxe Clinic, Chichester
cosmelan 2 Depigments & regulates
melan recovery, mesoestetic skincare at Mediluxe Clinic, Chichester
melan recovery Soothes & restores
melan 130, mesoestetic skincare at Mediluxe Clinic, Chichester
melan 130 Tinted SPF 50+
hydracream fusion, mesoestetic skincare at Mediluxe Clinic, Chichester
hydracream fusion Cream-to-oil cleanser
  1. Day 0

    Mask day

    Keep the mask on until the alarm Morgan sets, 6 to 8 hours after application. Remove with lukewarm water only, then apply melan recovery, and melan 130 if you are going out.

  2. Days 1–7

    Heal & soothe

    Morning: hydracream fusion, melan recovery, melan 130. Evening: hydracream fusion, melan recovery. No cosmelan 2 yet.

  3. Day 7 – 6 months

    Depigment & regulate

    Morning: hydracream fusion, a pea-sized amount of cosmelan 2, melan recovery, melan 130. Evening: hydracream fusion, cosmelan 2, melan recovery. One pot lasts around 6 weeks.

  4. Month 7 +

    Long-term maintenance

    Morning: hydracream fusion, melan tran3x concentrate and gel cream, melan 130. Evening: cosmelan 2, or skinretin 0.3% two nights a week. Peels and microneedling can be reintroduced.

Reapply melan 130 every 2–3 hours in daylight. Cosmelan 2 is dose-dependent: if your skin becomes too reactive, Morgan may ask you to use it once a day until it settles, then build back up.

Questions

Frequently asked.

What is Cosmelan?

Cosmelan is mesoestetic®’s professional depigmentation method, used on more than a million patients worldwide. It combines one intensive mask treatment in clinic with a guided home programme that fades existing pigmentation and helps regulate the cells that produce it.

How many sessions will I need?

Just one in clinic. The rest of the treatment happens at home, which is why your home routine and your reviews with Morgan are such an important part of your result.

How long is the Cosmelan programme?

From 6 weeks to 6 months, depending on your pigmentation. Lighter or more recent marks can respond within 6 weeks. Melasma and deep or long-standing pigmentation need the full 6-month protocol so pigment production stays regulated. Morgan recommends the right programme at your consultation.

Is there downtime?

The first 7 days are a healing phase. During the first month you may notice flaking, peeling, redness, mild swelling and tightness; peeling usually starts after 2 to 3 days. These are normal signs the treatment is working.

When will I see results?

Results are visible from the first week of treatment. Results continue to build across the programme, with the most significant change typically seen between day 120 and day 180.

Will my pigmentation come back?

Cosmelan is designed to lower that risk by regulating pigment production, not just lifting the surface. Completing the full programme, wearing SPF every day and following your maintenance routine all help keep results lasting.

Is Cosmelan suitable for darker skin?

Yes. Cosmelan is suitable for all Fitzpatrick skin types, I to VI, and is often chosen for deeper skin tones, where pigmentation is common and stronger peels and lasers carry more risk.

How long do I keep the mask on?

Between 6 and 8 hours, set by Morgan for your skin type and pigmentation, and never longer than 8 hours. You remove it at home with lukewarm water.

Can I have other treatments during Cosmelan?

A Melanostop Tranex peel is recommended 15 days before. After your session, chemical peels and microneedling are paused until month 7. The cosmelan 1 mask is used no more than once a year.

Who should not have Cosmelan?

Cosmelan is not suitable if you are pregnant, planning a pregnancy or breastfeeding, for children under 12, or if you have sunburn, a skin condition, open or healing wounds in the area, a bacterial, viral, fungal or herpetic infection (including cold sores), or an allergy to any of its ingredients. Tell us if you have taken isotretinoin (Roaccutane) in the last 6 months.

How much is Cosmelan in Chichester?

At Mediluxe Clinic, Cosmelan starts from £595 for the 6-Week Programme. The 6-Month Programme is £1,295 and includes your preparation peel. Both include your clinic session, home kit and reviews. Every price is on this page.

Discovery

Related treatments.

Personalised Care

Begin with an unhurried clinical consultation.

Every journey at Mediluxe starts with a full assessment and a transparent discussion of your goals, at Manor Farm Barns in Donnington with free parking outside.